Loading...
Systemic Akt1 Deletion after Tumor Onset in p53−/− Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration
Akt is frequently activated in human cancers. However, it is unknown whether systemic inhibition of a single Akt isoform could regress cancer progression in cancers that are not driven by Akt activation. We systemically deleted Akt1 after tumor onset in p53−/− mice, which develop tumors independentl...
Na minha lista:
Main Authors: | , , , , , |
---|---|
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Elsevier
2015-07-01
|
Serier: | Cell Reports |
Online adgang: | http://www.sciencedirect.com/science/article/pii/S221112471500683X |
Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|