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Gene-based multiple regression association testing for combined examination of common and low frequency variants in quantitative trait analysis

Multi-marker methods for genetic association analysis can be performed for common and low frequency SNPs to improve power. Regression models are an intuitive way to formulate multi-marker tests. In previous studies we evaluated regression-based multi-marker tests for common SNPs, and through identif...

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Detalhes bibliográficos
Main Authors: Yun Joo eYoo, Lei eSun, Shelley B. Bull
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-11-01
Colecção:Frontiers in Genetics
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Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00233/full
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