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Clique-Based Clustering of Correlated SNPs in a Gene Can Improve Performance of Gene-Based Multi-Bin Linear Combination Test

Gene-based analysis of multiple single nucleotide polymorphisms (SNPs) in a gene region is an alternative to single SNP analysis. The multi-bin linear combination test (MLC) proposed in previous studies utilizes the correlation among SNPs within a gene to construct a gene-based global test. SNPs are...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Yoo, Yun Joo, Kim, Sun Ah, Bull, Shelley B.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539439/
https://ncbi.nlm.nih.gov/pubmed/26346579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/852341
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