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Gene-based multiple regression association testing for combined examination of common and low frequency variants in quantitative trait analysis

Multi-marker methods for genetic association analysis can be performed for common and low frequency SNPs to improve power. Regression models are an intuitive way to formulate multi-marker tests. In previous studies we evaluated regression-based multi-marker tests for common SNPs, and through identif...

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Bibliographic Details
Main Authors: Yoo, Yun Joo, Sun, Lei, Bull, Shelley B.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824159/
https://ncbi.nlm.nih.gov/pubmed/24273553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00233
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