Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure

By jointly analyzing multiple variants within a gene, instead of one at a time, gene‐based multiple regression can improve power, robustness, and interpretation in genetic association analysis. We investigate multiple linear combination (MLC) test statistics for analysis of common variants under rea...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Yoo, Yun Joo, Sun, Lei, Poirier, Julia G., Paterson, Andrew D., Bull, Shelley B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245123/
https://ncbi.nlm.nih.gov/pubmed/27885705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22024
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