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SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.
BACKGROUND: CXC chemokines are induced by inflammatory stimuli in epithelial cells and some, like MIG/CXCL9, IP-10/CXCL10 and I-TAC/CXCL11, are antibacterial for Streptococcus pyogenes. METHODOLOGY/PRINCIPAL FINDINGS: SpeB from S. pyogenes degrades a wide range of chemokines (i.e. IP10/CXCL10, I-TAC...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science (PLoS)
2009-01-01
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Collection: | PLoS ONE |
Accès en ligne: | http://europepmc.org/articles/PMC2652026?pdf=render |
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