Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

Background: The selective estrogen receptor modulator tamoxifen, in combination with the Cre-ERT2 fusion protein, has been one of the mainstream methods to induce genetic recombination and has found widespread application in lineage tracing studies. Methods & results: Here, we report that tamoxi...

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Detalhes bibliográficos
Main Authors: Risheng Ye, Qiong A. Wang, Caroline Tao, Lavanya Vishvanath, Mengle Shao, Jeffery G. McDonald, Rana K. Gupta, Philipp E. Scherer
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-11-01
Colecção:Molecular Metabolism
Assuntos:
Tamoxifen
Cre recombinase
Adipose tissue
Lineage tracing
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212877815001593
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