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An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions
During viral RNA synthesis, Ebola virus (EBOV) nucleoprotein (NP) alternates between an RNA-template-bound form and a template-free form to provide the viral polymerase access to the RNA template. In addition, newly synthesized NP must be prevented from indiscriminately binding to noncognate RNAs. H...
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主要な著者: | , , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Elsevier
2015-04-01
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シリーズ: | Cell Reports |
オンライン・アクセス: | http://www.sciencedirect.com/science/article/pii/S2211124715003034 |
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