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Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression
Angulated femurs are present prenatally both in CYP26B1 deficient humans with a reduced capacity to degrade retinoic acid (RA, the active metabolite of vitamin A), and mice overexpressing vascular endothelial growth factor a (Vegfa). Since excessive ingestion of vitamin A is known to induce spontane...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2018-12-01
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| シリーズ: | Bone Reports |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S2352187218300391 |
| タグ: |
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