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Excessive dietary intake of vitamin A reduces skull bone thickness in mice
Calvarial thinning and skull bone defects have been reported in infants with hypervitaminosis A. These findings have also been described in humans, mice and zebrafish with loss-of-function mutations in the enzyme CYP26B1 that degrades retinoic acid (RA), the active metabolite of vitamin A, indicatin...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398668/ https://ncbi.nlm.nih.gov/pubmed/28426756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176217 |
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