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Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression
Angulated femurs are present prenatally both in CYP26B1 deficient humans with a reduced capacity to degrade retinoic acid (RA, the active metabolite of vitamin A), and mice overexpressing vascular endothelial growth factor a (Vegfa). Since excessive ingestion of vitamin A is known to induce spontane...
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| Publicado no: | Bone Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039751/ https://ncbi.nlm.nih.gov/pubmed/30003121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2018.06.006 |
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