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Rapamycin-Loaded mPEG-PLGA Nanoparticles Ameliorate Hepatic Steatosis and Liver Injury in Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and liver injury, and is the leading cause of chronic liver disease worldwide. There is an urgent need to develop novel pathophysiology-oriented therapy in human. Rapamycin (RAPA) has been recognized as a prom...

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Main Authors: Ruifang Zhao, Meilin Zhu, Shuang Zhou, Weiyue Feng, Hanqing Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Chemistry
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fchem.2020.00407/full
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