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Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

Biodistribution of nanoparticles is dependent on their physicochemical properties (such as size, surface charge, and surface hydrophilicity). Clear and systematic understanding of nanoparticle properties’ effects on their in vivo performance is of fundamental significance in nanoparticle design, dev...

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Detalhes bibliográficos
Main Authors: Li, Mingguang, Panagi, Zoi, Avgoustakis, Konstantinos, Reineke, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299578/
https://ncbi.nlm.nih.gov/pubmed/22419876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S23758
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