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Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

Biodistribution of nanoparticles is dependent on their physicochemical properties (such as size, surface charge, and surface hydrophilicity). Clear and systematic understanding of nanoparticle properties’ effects on their in vivo performance is of fundamental significance in nanoparticle design, dev...

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Autors principals: Li, Mingguang, Panagi, Zoi, Avgoustakis, Konstantinos, Reineke, Joshua
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299578/
https://ncbi.nlm.nih.gov/pubmed/22419876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S23758
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