Localised delivery of quercetin by thermo-sensitive PLGA-PEG-PLGA hydrogels for the treatment of brachial plexus avulsion

Accumulating evidence indicates that oxidative stress and inflammation are implicated in brachial plexus avulsion (BPA). Quercetin has anti-inflammatory, anti-oxidant, anti-apoptotic, and neuroprotective properties. This study investigated the therapeutic efficacy of a temperature-sensitive poly(D,L...

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Detalhes bibliográficos
Main Authors: Chao Huang, Chuan Fu, Zhi-Ping Qi, Wen-Lai Guo, Di You, Rui Li, Zhe Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-01-01
Colecção:Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:
PLGA-PEG-PLGA
brachial plexus avulsion
quercetin
nerve regeneration
oxidative damage
inflammatory response
Acesso em linha:https://www.tandfonline.com/doi/10.1080/21691401.2020.1770265
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