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<i>N</i>-Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells
The main mechanistic function of most chemotherapeutic drugs is mediated by inducing mitochondria-dependent apoptosis. Tumor cells usually respond to upregulate autophagy to eliminate impaired mitochondria for survival. Hypothetically, inhibiting autophagy might promote mitochondria-dependent apopto...
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| Glavni autori: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI AG
2019-07-01
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| Serija: | International Journal of Molecular Sciences |
| Teme: | |
| Online pristup: | https://www.mdpi.com/1422-0067/20/14/3415 |
| Oznake: |
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