The novel long noncoding RNA CRART16 confers cetuximab resistance in colorectal cancer cells by enhancing ERBB3 expression via miR-371a-5p

Abstract Background Long noncoding RNAs (lncRNAs) have been shown to participate in multiple biological processes and confer drug resistance. However, it remains unclear whether lncRNAs are involved in conferring cetuximab resistance in colorectal cancer (CRC) cells. Methods Cell Counting Kit-8 (CCK...

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Autori principali: Xiaoqian Zhang, Long Wen, Shanwen Chen, Junling Zhang, Yongchen Ma, Jianwen Hu, Taohua Yue, Jingui Wang, Jing Zhu, Dingfang Bu, Xin Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-03-01
Serie:Cancer Cell International
Soggetti:
Long noncoding RNA
CRART 16
Cetuximab
Resistance
miR-371a-5p
ERBB3
Accesso online:http://link.springer.com/article/10.1186/s12935-020-1155-9
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