Low expression of SPARC in gastric cancer-associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer

BACKGROUND: The aim of the present study was to clarify the correlations between SPARC expression in gastric cancer-associated fibroblasts (GCAFs) and the prognosis of patients with gastric cancer and to elucidate the role of GCAF-derived SPARC in stemness transformation and 5-fluorouracil resistanc...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Ma, Yongchen, Zhu, Jing, Chen, Shanwen, Ma, Ju, Zhang, Xiaoqian, Huang, Sixia, Hu, Jianwen, Yue, Taohua, Zhang, Junling, Wang, Pengyuan, Wang, Xin, Rong, Long, Guo, Hongjie, Chen, Guowei, Liu, Yucun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528188/
https://ncbi.nlm.nih.gov/pubmed/31139014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0844-8
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