Paxillin knockdown suppresses metastasis and epithelial-mesenchymal transition in colorectal cancer via the ERK signalling pathway

Paxillin (PXN) is a cytoplasmic protein that plays an important role in regulating focal adhesion, cytoskeletal rearrangements and cell motility. The present study aimed to investigate the role of PXN in the metastasis of human colorectal cancer (CRC) and its possible mechanisms. Immunohistochemical...

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Vydáno v:Oncol Rep
Hlavní autoři: Wen, Long, Zhang, Xiaoqian, Zhang, Junling, Chen, Shanwen, Ma, Yongchen, Hu, Jianwen, Yue, Taohua, Wang, Jingui, Zhu, Jing, Wu, Tao, Wang, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388420/
https://ncbi.nlm.nih.gov/pubmed/32705241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7687
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