Paxillin knockdown suppresses metastasis and epithelial-mesenchymal transition in colorectal cancer via the ERK signalling pathway

Paxillin (PXN) is a cytoplasmic protein that plays an important role in regulating focal adhesion, cytoskeletal rearrangements and cell motility. The present study aimed to investigate the role of PXN in the metastasis of human colorectal cancer (CRC) and its possible mechanisms. Immunohistochemical...

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Veröffentlicht in:Oncol Rep
Hauptverfasser: Wen, Long, Zhang, Xiaoqian, Zhang, Junling, Chen, Shanwen, Ma, Yongchen, Hu, Jianwen, Yue, Taohua, Wang, Jingui, Zhu, Jing, Wu, Tao, Wang, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388420/
https://ncbi.nlm.nih.gov/pubmed/32705241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7687
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