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Variation in CFTR-dependent 'β-sweating' among healthy adults.

The genetic disease cystic fibrosis (CF) results when mutations in the gene for the anion channel CFTR reduce CFTR's activity below a critical level. CFTR activity = N·PO·γ (number of channels x open probability x channel conductance). Small molecules are now available that partially restore CF...

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Main Authors: Lesje DeRose, Jeeyeon Kim, Miesha Farahmand, Meagan Y Shinbashi, Nam Soo Joo, Jeffrey J Wine
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2022-01-01
叢編:PLoS ONE
在線閱讀:https://doi.org/10.1371/journal.pone.0265432
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