Sweat rate analysis of ivacaftor potentiation of CFTR in non-CF adults

To determine if ivacaftor (Kalydeco) influences non-CF human CFTR function in vivo, we measured CFTR-dependent (C-sweat) and CFTR-independent (M-sweat) rates from multiple identified sweat glands in 8 non-CF adults. The two types of sweating were stimulated sequentially with intradermal injections o...

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Publicat a:Sci Rep
Autors principals: Kim, Jeeyeon, Farahmand, Miesha, Dunn, Colleen, Milla, Carlos E., Horii, Rina I., Thomas, Ewart A. C., Moss, Richard B., Wine, Jeffrey J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214959/
https://ncbi.nlm.nih.gov/pubmed/30389955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34308-8
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