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Variation in CFTR-dependent 'β-sweating' among healthy adults.
The genetic disease cystic fibrosis (CF) results when mutations in the gene for the anion channel CFTR reduce CFTR's activity below a critical level. CFTR activity = N·PO·γ (number of channels x open probability x channel conductance). Small molecules are now available that partially restore CF...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2022-01-01
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| Schriftenreihe: | PLoS ONE |
| Online Zugang: | https://doi.org/10.1371/journal.pone.0265432 |
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