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An empirical evaluation of imputation accuracy for association statistics reveals increased type-I error rates in genome-wide associations

<p>Abstract</p> <p>Background</p> <p>Genome wide association studies (GWAS) are becoming the approach of choice to identify genetic determinants of complex phenotypes and common diseases. The astonishing amount of generated data and the use of distinct genotyping platfo...

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書誌詳細
主要な著者: Pereira Alexandre C, Krieger José E, Pereira Tiago V, Oliveira Paulo SL, Almeida Marcio AA
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2011-01-01
シリーズ:BMC Genetics
オンライン・アクセス:http://www.biomedcentral.com/1471-2156/12/10
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