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The Relationship between Imputation Error and Statistical Power in Genetic Association Studies in Diverse Populations

Genotype-imputation methods provide an essential technique for high-resolution genome-wide association (GWA) studies with millions of single-nucleotide polymorphisms. For optimal design and interpretation of imputation-based GWA studies, it is important to understand the connection between imputatio...

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Autori principali: Huang, Lucy, Wang, Chaolong, Rosenberg, Noah A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775841/
https://ncbi.nlm.nih.gov/pubmed/19853241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.09.017
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