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Genotype imputation in a coalescent model with infinitely-many-sites mutation
Empirical studies have identified population-genetic factors as important determinants of the properties of genotype-imputation accuracy in imputation-based disease association studies. Here, we develop a simple coalescent model of three sequences that we use to explore the theoretical basis for the...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587719/ https://ncbi.nlm.nih.gov/pubmed/23079542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2012.09.006 |
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