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A Unifying Framework for Imputing Summary Statistics in Genome-Wide Association Studies

Methods to impute missing data are routinely used to increase power in genome-wide association studies. There are two broad classes of imputation methods. The first class imputes genotypes at the untyped variants, given those at the typed variants, and then performs a statistical test of association...

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Veröffentlicht in:J Comput Biol
Hauptverfasser: Wu, Yue, Eskin, Eleazar, Sankararaman, Sriram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081249/
https://ncbi.nlm.nih.gov/pubmed/32053016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0449
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