Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.

Misexpression of Polycomb repressive complex 1 (PRC1) components in human cells profoundly influences the onset of cellular senescence by modulating transcription of the INK4a tumor suppressor gene. Using tandem affinity purification, we find that CBX7 and CBX8, two Polycomb (Pc) homologs that repre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Goedele N Maertens, Selma El Messaoudi-Aubert, Tomas Racek, Julie K Stock, James Nicholls, Marc Rodriguez-Niedenführ, Jesus Gil, Gordon Peters
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2009-07-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC2713427?pdf=render
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge