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Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

<p>Abstract</p> <p>Background</p> <p>Compared to classical genotyping, targeted next-generation sequencing (<it>t</it>NGS) can be custom-designed to interrogate entire genomic regions of interest, in order to detect novel as well as known variants. To bring...

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Autori principali: ElSharawy Abdou, Forster Michael, Schracke Nadine, Keller Andreas, Thomsen Ingo, Petersen Britt-Sabina, Stade Björn, Stähler Peer, Schreiber Stefan, Rosenstiel Philip, Franke Andre
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-08-01
Serie:BMC Genomics
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Accesso online:http://www.biomedcentral.com/1471-2164/13/417
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