Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

<p>Abstract</p> <p>Background</p> <p>Compared to classical genotyping, targeted next-generation sequencing (<it>t</it>NGS) can be custom-designed to interrogate entire genomic regions of interest, in order to detect novel as well as known variants. To bring...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: ElSharawy Abdou, Forster Michael, Schracke Nadine, Keller Andreas, Thomsen Ingo, Petersen Britt-Sabina, Stade Björn, Stähler Peer, Schreiber Stefan, Rosenstiel Philip, Franke Andre
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-08-01
Colecção:BMC Genomics
Assuntos:
Two-stage mapping
Read-backmapping
Software performance
SNP discovery
Multiplexed targeted next-generation sequencing
Acesso em linha:http://www.biomedcentral.com/1471-2164/13/417
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados