Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

BACKGROUND: Compared to classical genotyping, targeted next-generation sequencing (tNGS) can be custom-designed to interrogate entire genomic regions of interest, in order to detect novel as well as known variants. To bring down the per-sample cost, one approach is to pool barcoded NGS libraries bef...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: ElSharawy, Abdou, Forster, Michael, Schracke, Nadine, Keller, Andreas, Thomsen, Ingo, Petersen, Britt-Sabina, Stade, Björn, Stähler, Peer, Schreiber, Stefan, Rosenstiel, Philip, Franke, Andre
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563481/
https://ncbi.nlm.nih.gov/pubmed/22913592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-417
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky