Whole genome and exome sequencing of monozygotic twins discordant for Crohn’s disease

BACKGROUND: Crohn’s disease (CD) is an inflammatory bowel disease caused by genetic and environmental factors. More than 160 susceptibility loci have been identified for IBD, yet a large part of the genetic variance remains unexplained. Recent studies have demonstrated genetic differences between mo...

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Main Authors: Petersen, Britt-Sabina, Spehlmann, Martina E, Raedler, Andreas, Stade, Björn, Thomsen, Ingo, Rabionet, Raquel, Rosenstiel, Philip, Schreiber, Stefan, Franke, Andre
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102722/
https://ncbi.nlm.nih.gov/pubmed/24996980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-564
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