Purpose-Oriented Antibody Libraries Incorporating Tailored CDR3 Sequences

The development of in vitro antibody selection technologies has allowed overcoming some limitations inherent to the hybridoma technology. In most cases, large repertoires of antibody genes have been assembled to create highly diversified libraries allowing the isolation of antibodies recognizing vir...

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Bibliographische Detailangaben
Hauptverfasser: Pauline Bonvin, Sophie Venet, Marie Kosco-Vilbois, Nicolas Fischer
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-05-01
Schriftenreihe:Antibodies
Schlagworte:
monoclonal antibody
phage display
antibody library
complementary determining region
cryptic site
pH-dependence
Online Zugang:http://www.mdpi.com/2073-4468/4/2/103
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