Efficient gene transfer into T lymphocytes by fiber-modified human adenovirus 5

Abstract Background The gene transduction efficiency of adenovirus to hematopoietic cells, especially T lymphocytes, is needed to be improved. The purpose of this study is to improve the transduction efficiency of T lymphocytes by using fiber-modified human adenovirus 5 (HAdV-5) vectors. Results Fou...

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Detalhes bibliográficos
Main Authors: Yun Lv, Feng-Jun Xiao, Yi Wang, Xiao-Hui Zou, Hua Wang, Hai-Yan Wang, Li-Sheng Wang, Zhuo-Zhuang Lu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-04-01
Colecção:BMC Biotechnology
Assuntos:
Gene therapy
Adenovirus 5 vector
Human hematopoietic cells
Acesso em linha:http://link.springer.com/article/10.1186/s12896-019-0514-x
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