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Canine Adenovirus Vectors: an Alternative for Adenovirus-Mediated Gene Transfer

Preclinical studies have shown that gene transfer following readministration of viral vectors is often inefficient due to the presence of neutralizing antibodies. Vectors derived from ubiquitous human adenoviruses may have limited clinical use because preexisting humoral and cellular immunity is fou...

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Bibliografiske detaljer
Main Authors: Kremer, Eric J., Boutin, Sylvie, Chillon, Miguel, Danos, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111562/
https://ncbi.nlm.nih.gov/pubmed/10590140
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