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Derivation of LIF-independent mouse iPS cells with modified Oct4

It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSCs for longer than 120 days with modified Oct4 alon...

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Detalhes bibliográficos
Main Authors: Hiroyuki Hirai, Meri Firpo, Nobuaki Kikyo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-09-01
Colecção:Stem Cell Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1873506115001087
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