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IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.
Infection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation mediated by CD4 Th17 cells, wherea...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2011-10-01
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| Серии: | PLoS Pathogens |
| Online-ссылка: | http://europepmc.org/articles/PMC3188523?pdf=render |
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