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IRAK-2 Regulates IL-1-Mediated Pathogenic Th17 Cell Development in Helminthic Infection

Infection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation mediated by CD4 Th17 cells, wherea...

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Detalles Bibliográficos
Main Authors: Smith, Patrick M., Jacque, Berri, Conner, James R., Poltorak, Alexander, Stadecker, Miguel J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188523/
https://ncbi.nlm.nih.gov/pubmed/21998578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002272
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