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Ploidy reductions in murine fusion-derived hepatocytes.
We previously showed that fusion between hepatocytes lacking a crucial liver enzyme, fumarylacetoacetate hydrolase (FAH), and wild-type blood cells resulted in hepatocyte reprogramming. FAH expression was restored in hybrid hepatocytes and, upon in vivo expansion, ameliorated the effects of FAH defi...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2009-02-01
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| Collection: | PLoS Genetics |
| Accès en ligne: | http://europepmc.org/articles/PMC2636893?pdf=render |
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