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IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.

The availability of a highly purified and well characterized circumsporozoite protein (CSP) is essential to improve upon the partial success of recombinant CSP-based malaria vaccine candidates. Soluble, near full-length, Plasmodium falciparum CSP vaccine antigen (CS/D) was produced in E. coli under...

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Detaylı Bibliyografya
Asıl Yazarlar: Robert Schwenk, Margot DeBot, Michael Porter, Jennifer Nikki, Lisa Rein, Roberta Spaccapelo, Andrea Crisanti, Paul D Wightman, Christian F Ockenhouse, Sheetij Dutta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2014-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC4208815?pdf=render
Etiketler: Etiketle
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