IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.

The availability of a highly purified and well characterized circumsporozoite protein (CSP) is essential to improve upon the partial success of recombinant CSP-based malaria vaccine candidates. Soluble, near full-length, Plasmodium falciparum CSP vaccine antigen (CS/D) was produced in E. coli under...

Full description

Saved in:

Bibliographic Details
Main Authors:	Robert Schwenk, Margot DeBot, Michael Porter, Jennifer Nikki, Lisa Rein, Roberta Spaccapelo, Andrea Crisanti, Paul D Wightman, Christian F Ockenhouse, Sheetij Dutta
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4208815?pdf=render
Tags:	Add Tag No Tags, Be the first to tag this record!

IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.

Similar Items