Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.

Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have been limited to adolescent and adult populations where brain plasticity durin...

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Huvudupphovsmän: Robert J Lipinski, Hunter T Holloway, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Gary P Cofer, Francois Budin, Joshua L Everson, G Allan Johnson, Kathleen K Sulik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4105496?pdf=render
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