Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.

Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have been limited to adolescent and adult populations where brain plasticity durin...

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Главные авторы: Robert J Lipinski, Hunter T Holloway, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Gary P Cofer, Francois Budin, Joshua L Everson, G Allan Johnson, Kathleen K Sulik
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2014-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4105496?pdf=render
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