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Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation.

Vascular endothelial growth factor (VEGF) signal transduction is central to angiogenesis in development and in pathological conditions such as cancer, retinopathy and ischemic diseases. However, no detailed mass-action models of VEGF receptor signaling have been developed. We constructed and validat...

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Detalhes bibliográficos
Main Authors: Wan Hua Tan, Aleksander S Popel, Feilim Mac Gabhann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3689841?pdf=render
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