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Estimation of parent specific DNA copy number in tumors using high-density genotyping arrays.
Chromosomal gains and losses comprise an important type of genetic change in tumors, and can now be assayed using microarray hybridization-based experiments. Most current statistical models for DNA copy number estimate total copy number, which do not distinguish between the underlying quantities of...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2011-01-01
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| Edice: | PLoS Computational Biology |
| On-line přístup: | http://europepmc.org/articles/PMC3029233?pdf=render |
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