Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

<p>Abstract</p> <p>Background</p> <p>Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte...

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Main Authors: Koppelmann Tal, Pollak Yulia, Mogilner Jorge, Bejar Jacob, Coran Arnold G, Sukhotnik Igor
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2012-04-01
Series:BMC Gastroenterology
Assuntos:
Methotrexate
Mucositis
Intestine
Arginine
Rat
Acceso en liña:http://www.biomedcentral.com/1471-230X/12/41
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