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Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

BACKGROUND: Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte proliferation and apoptosis following methotrexate (MTX...

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Detalhes bibliográficos
Main Authors: Koppelmann, Tal, Pollak, Yulia, Mogilner, Jorge, Bejar, Jacob, Coran, Arnold G, Sukhotnik, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355056/
https://ncbi.nlm.nih.gov/pubmed/22545735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-41
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