Glutamine attenuates the inhibitory effect of methotrexate on TLR signaling during intestinal chemotherapy-induced mucositis in a rat

Toll-like receptor 4 (TLR-4) is crucial in maintaining intestinal epithelial homeostasis, participates in a vigorous signaling process and heightens inflammatory cytokine output. The objective of this study was to determine the effects of glutamine (GLN) on TLR-4 signaling in intestinal mucosa durin...

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Autori principali: Sukhotnik, Igor, Pollak, Yulia, Coran, Arnold G, Pilatov, Janna, Bejar, Jacob, Mogilner, Jorge G, Berkowitz, Drora
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005622/
https://ncbi.nlm.nih.gov/pubmed/24742067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-11-17
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