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The Role of Wnt/β-Catenin Signaling in Enterocyte Turnover during Methotrexate-Induced Intestinal Mucositis in a Rat

BACKGROUND/AIMS: Intestinal mucositis is a common side-effect in patients who receive aggressive chemotherapy. The Wnt signaling pathway is critical for establishing and maintaining the proliferative compartment of the intestine. In the present study, we tested whether Wnt/β-catenin signaling is inv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sukhotnik, Igor, Geyer, Tatiana, Pollak, Yulia, Mogilner, Jorge G., Coran, Arnold G., Berkowitz, Drora
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222808/
https://ncbi.nlm.nih.gov/pubmed/25375224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110675
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