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iRegulon: from a gene list to a gene regulatory network using large motif and track collections.
Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. We developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying a co-expressed gene set using cis-regula...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2014-07-01
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| Serie: | PLoS Computational Biology |
| Accesso online: | http://europepmc.org/articles/PMC4109854?pdf=render |
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